Detalhe da pesquisa
1.
GBT021601 improves red blood cell health and the pathophysiology of sickle cell disease in a murine model.
Br J Haematol
; 202(1): 173-183, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36960712
2.
The Molecular Size of Bioengineered Oxygen Carriers Determines Tissue Oxygenation in a Hypercholesterolemia Guinea Pig Model of Hemorrhagic Shock and Resuscitation.
Mol Pharm
; 20(11): 5739-5752, 2023 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37843033
3.
Changes in oxygen delivery during experimental models of cerebral malaria.
Exp Parasitol
; 254: 108608, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37673369
4.
The Double-Edged Sword of Erythrocytes in Health and Disease via Their Adhesiveness.
Int J Mol Sci
; 24(12)2023 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37373527
5.
Hyperspectral wide-field-of-view imaging to study dynamic microcirculatory changes during hypoxia.
Am J Physiol Heart Circ Physiol
; 323(1): H49-H58, 2022 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35522555
6.
Increased hemoglobin affinity for oxygen with GBT1118 improves hypoxia tolerance in sickle cell mice.
Am J Physiol Heart Circ Physiol
; 321(2): H400-H411, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213392
7.
Negative pressure increases microvascular perfusion during severe hemorrhagic shock.
Microvasc Res
; 134: 104125, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33346023
8.
Purification and analysis of a protein cocktail capable of scavenging cell-free hemoglobin, heme, and iron.
Transfusion
; 61(6): 1894-1907, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33817808
9.
Safety profile of high molecular weight polymerized hemoglobins.
Transfusion
; 61(1): 212-224, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33104250
10.
Tumor vascular status controls oxygen delivery facilitated by infused polymerized hemoglobins with varying oxygen affinity.
PLoS Comput Biol
; 16(8): e1008157, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32817659
11.
RRx-001 Increases Erythrocyte Preferential Adhesion to the Tumor Vasculature.
Int J Mol Sci
; 22(9)2021 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33946824
12.
Hemoglobin ß93 Cysteine Is Not Required for Export of Nitric Oxide Bioactivity From the Red Blood Cell.
Circulation
; 139(23): 2654-2663, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30905171
13.
Apohemoglobin-haptoglobin complex attenuates the pathobiology of circulating acellular hemoglobin and heme.
Am J Physiol Heart Circ Physiol
; 318(5): H1296-H1307, 2020 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32302494
14.
Enzyme promiscuity drives branched-chain fatty acid synthesis in adipose tissues.
Nat Chem Biol
; 14(11): 1021-1031, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30327559
15.
Red Blood Cell Metabolic Responses to Torpor and Arousal in the Hibernator Arctic Ground Squirrel.
J Proteome Res
; 18(4): 1827-1841, 2019 04 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30793910
16.
Cardioprotective Effect of Phase 3 Clinical Anticancer Agent, RRx-001, in Doxorubicin-Induced Acute Cardiotoxicity in Mice.
Mol Pharm
; 16(7): 2929-2934, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31038318
17.
Do Skeletal Dynamics Mediate Sugar Uptake and Transport in Human Erythrocytes?
Biophys J
; 114(6): 1440-1454, 2018 03 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-29590601
18.
Platelet inhibitory effects of the Phase 3 anticancer and normal tissue cytoprotective agent, RRx-001.
J Cell Mol Med
; 22(10): 5076-5082, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30010241
19.
TGF-ß: the apex predator of immune checkpoints.
Future Oncol
; 19(30): 2013-2015, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37503560
20.
Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice.
Proc Natl Acad Sci U S A
; 112(33): 10425-30, 2015 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26240367